This article is a couple of years old, but the advice is still relevant, such as...
A good way to get yourself back into working is by volunteering or looking for part-time or project work. You get the benefits of networking, as well as bolstering your resume with recent experience.
"Before you reach out to anyone, have a brief elevator pitch ready--a 30-second spiel that sums up what kind of work you're looking for and what your experience is. End the pitch by asking, Do you know of anyone I should talk to? Never ask if they have a job to offer themselves. People will know what you want, and if they feel comfortable telling you about an opening they know of, they will."
Before you begin your job search in earnest, make sure you have the support you need, such as childcare incase you are invited to interview.
Never apologize for having taken time away from your career to raise children. If asked about it, answer succinctly and move on.
Get together with others who are in the same situation and practice interviewing.
Read the full article here.